Table 3 Summary of each sociodemographic, morphological, behavioral, and biochemical variables. Mean values ± standard deviation (number of subjects) and post hoc comparison of means for the demographics within groups significant difference (control group as reference).

Age [years]*

66 ± 8.4

72 ± 4.8*

77 ± 6.1*

Education [years]*

15 ± 2.2

13 ± 2.4*

13 ± 3*

Female, N (%)

53 (69%)

19 (61%)

8 (62%)

Morphometrical

Cortical Thickness [mm]*

2.5 ± 0.099

2.5 ± 0.088*

2.4 ± 0.079*

Total Area [mm]

98000 ± 7800

97000 ± 8200

95000 ± 9300

Exposed Area [mm2]

37000 ± 2400

37000 ± 2600

37000 ± 3000

k*

0.30 ± 0.0095

0.29 ± 0.0094*

0.28 ± 0.01*

K (\(log_{10}{k}\))*

− 0.52 ± 0.014

− 0.53 ± 0.014*

− 0.55 ± 0.015*

Behavioral

 Cognitive Index*

0.21 ± 0.64

− 1.5 ± 1.3*

− 3.4 ± 1.5*

 RAVLT A7/A5*

0.82 ± 0.18

0.53 ± 0.31*

0.24 ± 0.31*

 TMT B-A*

59 ± 48

130 ± 110*

230 ± 130*

 Digit Span Backward*

5.8 ± 1.7

4.6 ± 1.6*

3.8 ± 1.4*

Biochemical (CSF)

 Lipoxin [pg/mL]*

130 ± 62 (28)

120 ± 51 (11)

79 ± 74 (6)*

 A\(\beta \)1-40 [pg/mL]

4200 ± 1900 (29)

5000 ± 2600 (11)

5700 ± 1700 (6)

 A\(\beta \)1-42 [pg/mL]*

530 ± 240 (29)

450 ± 320 (11)

280 ± 60 (6)*

 t-Tau [pg/mL]*

350 ± 190 (29)

470 ± 200 (11)

630 ± 280 (6)*