Table 3 Performance metrics with Test C for MP-CNN model vs SP-CNN model.
Algorithm | Model | AUROC (95% CI) | Accuracy (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) |
|---|---|---|---|---|---|---|---|
ResNet50 | MP-CNN | 0.795 (0.782–0.808) | 0.667 (0.631–0.703) | 0.930 (0.902–0.958) | 0.404 (0.308–0.500) | 0.612 (0.578–0.646) | 0.856 (0.829–0.883) |
SP-CNN(Neu) | 0.769 (0.748–0.790) | 0.642 (0.614–0.670) | 0.922 (0.897–0.947) | 0.362 (0.284–0.440) | 0.593 (0.569–0.616) | 0.826 (0.800–0.852) | |
SP-CNN(Flx) | 0.773 (0.747–0.798) | 0.651 (0.635–0.667) | 0.900 (0.867–0.933) | 0.402 (0.340–0.464) | 0.602 (0.585–0.619) | 0.806 (0.778–0.883) | |
SP-CNN(Ext) | 0.742* (0.726–0.758) | 0.661 (0.638–0.684) | 0.886 (0.848–0.924) | 0.436 (0.366–0.506) | 0.612 (0.591– 0.634) | 0.798 (0.760–0.836) | |
VGG19 | MP-CNN | 0.772 (0.743–0.801) | 0.683 (0.657–0.709) | 0.920 (0.879–0.961) | 0.446 (0.377–0.515) | 0.625 (0.602–0.649) | 0.857 (0.800–0.914) |
SP-CNN(Neu) | 0.776* (0.754–0.798) | 0.667 (0.642–0.692) | 0.926 (0.883–0.969) | 0.408 (0.329–0.486) | 0.612 (0.589–0.648) | 0.883 (0.838–0.928) | |
SP-CNN(Flx) | 0.743 (0.707–0.780) | 0.648 (0.624–0.672) | 0.920 (0.872–0.968) | 0.376 (0.315–0.437) | 0.596 (0.579–0.635) | 0.859 (0.808–0.911) | |
SP-CNN(Ext) | 0.721* (0.695–0.747) | 0.665 (0.635–0.695) | 0.858 (0.794–0.922) | 0.472 (0.395–0.549) | 0.620 (0.595–0.645) | 0.780 (0.714–0.847) | |
VGG16 | MP-CNN | 0.775 (0.743–0.807) | 0.667 (0.636–0.698) | 0.952 (0.935–0.969) | 0.382 (0.313–0.451) | 0.608 (0.582–0.633) | 0.890 (0.856–0.924) |
SP-CNN(Neu) | 0.769 (0.727–0.811) | 0.630 (0.600–0.660) | 0.984 (0.971–0.997) | 0.276 (0.207–0.345) | 0.577 (0.556–0.599) | 0.951 (0.917–0.984) | |
SP-CNN(Flx) | 0.743 (0.695–0.790) | 0.641 (0.606–0.675) | 0.903 (0.883–0.923) | 0.384 (0.322–0.446) | 0.590 (0.566–0.615) | 0.796 (0.735–0.857) | |
SP-CNN(Ext) | 0.725 (0.689–0.761) | 0.670 (0.652–0.688) | 0.902 (0.876–0.928) | 0.438 (0.394–0.482) | 0.617 (0.601–0.632) | 0.820 (0.784–0.856) | |
EfficientNet-B1 | MP-CNN | 0.748 (0.727–0.768) | 0.634 (0.624–0.644) | 0.944 (0.934–0.954) | 0.324 (0.306–0.342) | 0.583 (0.576– 0.590) | 0.853 (0.830–0.876) |
SP-CNN(Neu) | 0.726 (0.698–0.754) | 0.604 (0.581–0.627) | 0.920 (0.896–0.944) | 0.288 (0.242–0.334) | 0.564 (0.548–0.580) | 0.783 (0.733–0.834) | |
SP-CNN(Flx) | 0.726* (0.701–0.751) | 0.631 (0.603–0.659) | 0.946 (0.938–0.954) | 0.316 (0.253–0.379) | 0.581 (0.561–0.601) | 0.852 (0.840–0.864) | |
SP-CNN(Ext) | 0.700 (0.669–0.732) | 0.623 (0.597–0.649) | 0.888 (0.858–0.918) | 0.358 (0.293–0.423) | 0.581 (0.562–0.601) | 0.762 (0.728–0.796) |