Table 1 Detailed characteristics of the studies included.
References | Jie et al.68 | Zuo et al.67 | Karlsson et al.59 | Baragetti et al.60 | Mitra et al.61 | Million et al.66 |
|---|---|---|---|---|---|---|
Origin | Gut | Gut | Gut | Gut | Plaque | Blood culture |
Type of CVD | Atherosclerosis | Atrial fibrillation | Atherosclerosis | Atherosclerosis | Ischemic attacks | Infective endocarditis |
Country | China | China | Sweden | Italy | Singapore | France |
Number of participants (age range) | 405 (61 years) | 100 (57–71 years) | 410 (65 ± 5 years) | 345 (67 ± 11 years) | 22 (not mentioned) | 10 (not mentioned) |
Number of samples analysed | 214 | 44 | 26 | 165 | 7 | 4 |
Average percentage of reads identified to species-level (min–max) | 88.0 (21–97) | 93.3 (86–96) | 77.30 (53–87) | 95.18 (63–100) | 13.28 (13–15) | 39 (16–84) |
Average percentage of bacteria identified to species-level (min–max) | 87.43 (68–96) | 93.09 (86–97) | 76.15 (53–86) | 80.12 (18–96) | 11 (10–12) | 34.75 (13–83) |
Average number of reads per sample | 2.6 × 107 | 2.5 × 107 | 3.0 × 107 | 1.3 × 107 | 3.3 × 106 | 1.3 × 107 |
Three most abundant bacterial species | Escherichia coli, Klebsiella pneumoniae, Bifidobacterium longum | Escherichia coli, Bifidobacterium longum, Klebsiella pneumoniae | Escherichia coli, Staphylococcus haemolyticus, Pseudomonas fluorescens | Escherichia coli, Bifidobacterium longum, Klebsiella pneumoniae | Acinetobacter baumannii, Mycobacterium tuberculosis, Enterococcus faecalis | Moraxella osloensis, Acinetobacter baumannii, Enhydrobacter aerosaccus |
Most abundant oral bacterial species | Streptococcus salivarius | Streptococcus salivarius | Neisseria meningitidis | Streptococcus salivarius | Lactobacillus crispatus | Cutibacterium acnes |
