Table 3 Sensitivity analysis censoring the NED by multivariable Cox regression for mortality by centile of TC.

From: Association between total cholesterol levels and all-cause mortality among newly diagnosed patients with cancer

 

No. of patients

Events

Person-years

Incidence rate (per 10,000 py)

Age and sex-adjusted HR (95% CI)

Multivariable-adjusted HR (95% CI)

1st–5th (≤ 97 mg/dL)

3012

894

10,467

854.2

1.86 (1.71–2.02)

1.60 (1.46–1.74)

6th–20th (97–128 mg/dL)

9217

2051

32,517

630.7

1.52 (1.42–1.62)

1.29 (1.20–1.38)

21st–40th (129–151 mg/dL)

12,006

2030

44,129

460.0

1.20 (1.12–1.29)

1.08 (1.01–1.16)

41st–60th (152–171 mg/dL)

11,467

1690

42,565

397.0

1.13 (1.05–1.21)

1.06 (0.99–1.13)

61st–80th (172–196 mg/dL)

11,903

1466

44,807

327.2

Reference

Reference

81st–95th (197–233 mg/dL)

8690

996

33,300

299.1

0.96 (0.88–1.04)

1.03 (0.95–1.11)

96th–100th (> 233 mg/dL)

2922

410

11,228

365.1

1.25 (1.12–1.39)

1.35 (1.21–1.51)

  1. Multivariable-adjusted model was adjusted for age, sex, BMI, use of lipid-lowering agents, presence of CKD, DM, and HTN, smoking status, alcohol consumption, and cancer type.
  2. CKD chronic kidney disease, DM diabetes mellitus, HR hazard ratio, HTN hypertension, NED no evidence of disease, TC total cholesterol, CI confidence interval.
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