Table 1 Baseline characteristics of patients with MG who underwent kidney biopsy.

From: Development and validation of a diagnostic nomogram model for predicting monoclonal gammopathy of renal significance

Clinical indices

MGUS Lesions (n = 231)

MGRS Lesions (n = 116)

p value

Male, n (%)

78 (33.8)

39 (33.6)

1

Age, years

55.13 (12.73)

60.18 (9.22)

 < 0.001

Edema, n (%)

180 (77.9)

86 (74.1)

0.537

Nausea, n (%)

46 (19.9)

40 (34.5)

0.01

Hypertension, n (%)

126 (54.5)

47 (40.5)

0.034

Hematuria

113 (48.9)

30 (25.9)

 < 0.001

Hemoglobin (g/L)

117.20 (22.76)

118.18 (25.67)

0.717

BUN (mmol/L)

12.39 (21.89)

9.37 (7.18)

0.15

Creatinine (μmol/L)

152.32 (142.43)

150.49 (164.71)

0.915

UA (μmol/L)

365.95 (123.72)

365.60 (196.61)

0.984

Albumin (g/L)

29.57 (8.72)

27.81 (8.67)

0.076

eGFR (mL/min per 1.73 m2)

68.66 (72.89)

67.84 (84.29)

0.161

24hTP (g/day)

4.60 (4.15)

5.52 (3.62)

0.043

CRP (mmol/L)

12.18 (29.80)

5.98 (10.71)

0.035

ESR (mm/h)

46.55 (36.70)

50.61 (35.49)

0.343

Complement 3 (g/L)

1.11 (0.29)

1.16 (0.31)

0.173

Complement 4 (g/L)

0.28 (0.12)

0.31 (0.14)

0.087

Abnormal FLC ratio

38 (16.5)

87 (75.0)

 < 0.001

dFLC (mg/L)

62.13 (320.37)

874.79 (2220.76)

 < 0.001

  1. Values of continuous variables are described as mean ± SD or median (interquartile range) depending on the distribution, and categorical variables described as count (%). Hematuria positive urinary red blood cells > 5.
  2. BUN Serum urea nitrogen, UA serum uric acid, eGFR estimated glomerular filtration rate, 24hTP 24-h urine total protein, CRP C-reactive protein, ESR erythrocyte sedimentation rate, FLC free light chain, dFLC free light chain difference.