Table 3 Multivariable logistic regression analyses between the size, location, and pedunculated type of advanced adenoma with the false negative results of the FOBT.

Variable	Event, n	Crude model^a		Model 1^b		Model 2^c
Variable	Event, n	OR 95% CI	P-value	OR 95% CI	P-value	OR 95% CI	P-value
Size, mm	162/342 (47.4)	0.43 (0.28–0.67)	< 0.001	0.43 (0.28–0.66)	< 0.001	0.49 (0.31–0.77)	0.002
Location
Right-sided	64/106 (60.4)	1 (Reference)		1 (Reference)		1 (Reference)
Left-sided	98/236 (41.5)	0.47 (0.29–0.74)	0.001	0.47 (0.29–0.75)	0.001	0.53 (0.31–0.89)	0.016
Pedunculated type
No	127/248 (51.2)	1 (Reference)		1 (Reference)		1 (Reference)
Yes	35/94 (37.2)	0.57 (0.35–0.92)	0.022	0.56 (0.34–0.92)	0.021	0.73 (0.43–1.24)	0.246

OR odds ratio, CI confidence interval, PLT platelets, HGB hemoglobin, TG triglyceride, CRC colorectal cancer, HLP hyperlipidemia, DM diabetes mellitus.
^aUnadjusted; ^bAdjusted for sex and age; ^cAdjusted for sex, age, weight, smoking, drinking, antiplatelet anticoagulant use, size, location, pedunculated type, high-grade dysplasia, villous component, TG, PLT, HGB, family history of CRC, hypertension, HLP, and DM except for the variable itself.

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