Table 6 Depicts an in vitro time-kill kinetics study that compares the growth of Staphylococcus aureus, Escherichia coli, and Candida albicans treated with 210 µg/ml ZnO/MnO nanocomposite to untreated controls and measures viable counts (log10CFU/ml ± SD) as well as reductive percentage (% ± SD).
Cultivation period (hr) | Pathogens treated with 210 µg/ml of ZnO/MnO nanocomposite | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Staphylococcus aureus | Escherichia coli | Candida albicans | |||||||
Viable counts (log10CFU/ml ± SD) | Growth reduction (% ± SD) | Viable counts (log10CFU/ml ± SD) | Growth reduction (% ± SD) | Viable counts (log10CFU/ml ± SD) | Biomass reduction (% ± SD) | ||||
Control | Treated | Control | Treated | Control | Treated | ||||
0 | 0.36 ± 0.04 | 0.32 ± 0.07 | 0.3 ± 0.23 | 0.25 ± 0.04 | 0.41 ± 0.09 | 0.35 ± 0.09 | |||
6 | 1.98 ± 0.48 | 0.65 ± 0.47 | 52.02 ± 4.26 | 1.06 ± 0.78 | 0.59 ± 0.54 | 44.34 ± 5.45 | 1.48 ± 0.12 | 0.94 ± 1.24 | 36.32 ± 1.39 |
12 | 2.76 ± 0.98 | 0.95 ± 0.74 | 80.07 ± 3.12 | 3.21 ± 1.23 | 1.09 ± 0.04 | 66.04 ± 4.12 | 1.98 ± 0.07 | 0.96 ± 0.09 | 51.53 ± 2.98 |
18 | 4.14 ± 1.36 | 1.13 ± 0.95 | 86.62 ± 6.45 | 4.56 ± 1.60 | 1.3 ± 0.68 | 71.49 ± 3.12 | 2.51 ± 1.13 | 1.09 ± 1.87 | 56.60 ± 3.89 |
24 | 4.89 ± 1.45 | 1.48 ± 0.71 | 94.27 ± 2.59 | 4.98 ± 0.35 | 1.21 ± 0.85 | 75.70 ± 2.36 | 3.44 ± 0.78 | 1.26 ± 0.19 | 63.33 ± 2.12 |
30 | 5.35 ± 2.15 | 1.54 ± 0.93 | 95.51 ± 2.84 | 5.25 ± 1.24 | 1.19 ± 0.78 | 77.33 ± 2.75 | 4.39 ± 1.36 | 1.15 ± 0.57 | 73.793 ± 1.09 |
36 | 5.73 ± 1.97 | 1.28 ± 1.07 | 96.86 ± 5.23 | 5.5 ± 1.40 | 1.01 ± 0.74 | 81.64 ± 3.12 | 5.29 ± 0.97 | 1.18 ± 0.16 | 77.71 ± 3.89 |