Table 1 Image acquisition parameters, measured values of noise as well as the signal and SNR of the totally illuminated area (Stotal), and the segmented high intensity (Shigh) and low intensity parts (Slow) (cf. Figure 3). The fourth row presents the time required for acquiring the number of k-space lines after one block of illumination. All images were acquired with a FoV of 9 × 9 mm2 (cf. Figure 3) and a four-fold oversampling, i.e. four-fold number of k-space lines as compared to the actual resolution. The first two echoes of each echo train were not used for image encoding to reduce the impact of B0 and B1 artifacts.

From: Detection of sub-nmol amounts of the antiviral drug favipiravir in 19F MRI using photo-chemically induced dynamic nuclear polarization

Figure

3a/e

3b/f

3c/g

3d/h

Image acquisition parameters

 Actual resolution in plane (FoV 9 × 9 mm2)

9 × 9

1 mm2/pix

17 × 17

(0.53)2 mm2/pix

17 × 17

(0.53)2 mm2/pix

23 × 23

(0.39)2 mm2/pix

 Acquisition

(per illumination)

Full image

(36 k-space lines)

Full image

(68 k-space lines)

Full image/4

(17 k-space lines)

Full image/2

(46 k-space lines)

 Illumination

1 × 4 s

1 × 4 s

4 × 4 s

2 × 4 s

 Acquisiton time per illumination

36 × 4 ms + 8 ms = 152 ms

68 × 4 ms + 8 ms = 280 ms

17 × 4 ms + 8 ms = 76 ms

46 × 4 ms + 8 ms = 192 ms

 Averages

8

16

16

16

Signal-to-noise ratio (SNR)

 Noise/μV

2.73 × 10–4

4.27 × 10–4

5.0 × 10–4

6.5 × 10–4

 Mean Stotal/μV

 SNRtotal

1.68 × 10–3

6.15

2.02 × 10–3

4.73

3.07 × 10–3

6.14

2.77 × 10–3

4.26

 Mean Shigh/μV

 SNRhigh

3.01 × 10–3

11.03

3.78 × 10–3

8.85

5.05 × 10–3

10.1

4.68 × 10–3

7.2

 Mean Slow/μV

 SNRlow

1.48 × 10–3

5.42

1.79 × 10–3

4.19

2.99 × 10–3

5.98

2.65 × 10–3

4.0

 Signalmin/μV (blue)

 Signalmax/μV (red)

6.39 × 10–5

3.17 × 10–3

1.71 × 10–5

3.96 × 10–3

2.04 × 10–5

5.481 × 10–3

6.14 × 10–5

5.24 × 10–3