Figure 1

Differentially expressed circRNA identified by transcriptome sequencing analysis. (A) Volcano plot of the differentially expressed circRNA identified by transcriptome sequencing analysis; (B) Demography of the differentially expressed circRNA, including 24 upregulated circRNAs and 49 downregulated circRNAs; (C) Heatmap of the differentially expressed circRNA identified by transcriptome sequencing analysis; (D) The expression of hsa_circ_0081065 was detected by RT-qPCR which was consistent with the transcriptome sequencing results, ****P < 0.0001, IH group Vs Control group; (E, F) GO and KEGG enrichment analysis for the differentially expressed circRNAs.