Table 4 Adjusted comparison of endotype survival outcomes.

From: Identification of clinically relevant patient endotypes in traumatic brain injury using latent class analysis

Model

Variable

Odds Ratio

95% CI

P-value

HE as reference

HFA

0.803

0.747–0.862

 < 0.001***

RFH

0.889

0.821–0.964

0.004**

AA

0.999

0.935–1.066

0.968

HTN

0.962

0.919–1.007

0.095

Age (years)

0.991

0.991–0.992

 < 0.001***

GCS score

1.028

1.024–1.031

 < 0.001***

Male sex

0.999

0.966–1.033

0.944

HFA as reference

HE

1.246

1.159–1.339

 < 0.001***

RFH

1.108

1.011–1.214

0.0284*

AA

1.244

1.139–1.359

 < 0.001***

HTN

1.198

1.123–1.279

 < 0.001***

RFH as reference

HFA

0.903

0.824–0.989

0.028*

HE

1.125

1.038–1.219

0.004**

AA

1.123

1.021–1.235

0.017*

HTN

1.082

1.004–1.166

0.040*

AA as reference

HFA

0.804

0.736–0.878

 < 0.001***

HE

1.001

0.938–1.069

0.968

RFH

0.890

0.810–0.979

0.017*

HTN

0.963

0.899–1.032

0.288

HTN as reference

HFA

0.834

0.782–0.891

 < 0.001***

HE

1.040

0.993–1.088

0.095

RFH

0.924

0.857–0.996

0.040*

AA

1.038

0.969–1.112

0.288

  1. Comparison of survival rates across the five stable comorbidity endotypes after adjustment by age, sex, and Glasgow coma scale (GCS) using multivariate logistic regression. The base regression model uses the HE endotype as the reference for the endotype variable in survival odds ratio calculations. Models using the other endotypes as reference are also reported for comparison. Odds ratio for age, sex, and GCS are omitted in these models as they remained constant for all models.
  2. HFA: Heart failure and arrhythmia, HE Healthy, RFH Renal failure with hypertension, AA Alcohol abuse, HTN Hypertension.
  3. Significance codes: “***”: ≤ 0.001, “**”: ≤ 0.01, “*”: ≤ 0.05.
Back to article page