Table 2 Weighted selected characteristics of study population in female and male, NHANES (Weighted N = 40,804,313).

From: The association between lipid biomarkers and osteoarthritis based on the National Health and Nutrition Examination Survey and Mendelian randomization study

Characteristics

Total

No-OA

OA

P value

Sex, n (%)

 Female

1993 (49.76)

1676 (53.74)

317 (38.42)

Ref

 Male

1713 (50.24)

1194 (46.26)

519 (61.58)

 < 0.0001

Age (year), mean (SD)

61.80 (0.19)

60.81 (0.21)

64.6 1(0.36)

 < 0.0001

BMI, mean (SD)

28.42 (0.13)

27.94 (0.14)

29.78 (0.26)

 < 0.0001

Race/ethnicity, n (%)

 White

1946 (79.11)

1382 (76.61)

564 (86.24)

Ref

 Mexican

462 ( 3.88)

396 (4.47)

66 (2.19)

 < 0.0001

 Black

624 ( 7.65)

521 (8.61)

103 (4.90)

 < 0.0001

 Other

674 ( 9.37)

571 (10.31)

103 (6.68)

 < 0.0001

Marital status, n (%)

 Married

2282 (66.44)

1778 (66.57)

504 (66.05)

Ref

 Living with partner

133 ( 3.22)

108 (3.48)

25 (2.49)

0.431

 Separated

108 ( 1.61)

96 (1.94)

12 (0.67)

0.019

 Divorced

510 (13.48)

397 (13.64)

113 (13.01)

0.975

 Widowed

425 ( 9.16)

290 ( 7.96)

135 (12.58)

 < 0.0001

 Never married

248 ( 6.09)

201 (6.41)

47 (5.19)

0.316

Education, n (%)

 Under high school

768 (11.11)

637 (11.51)

131( 9.96)

Ref

 High school or equivalent

837 (23.19)

636 (23.68)

201 (21.80)

0.002

 Above high school

2101 (65.70)

1597 (64.81)

504 (68.24)

 < 0.0001

Poverty, mean (SD)

3.51 (0.05)

3.52 (0.05)

3.45 (0.10)

0.43

Smoking, n (%)

Never

1849 (50.86)

1455 (52.02)

394 (47.54)

Ref

 Former

1312 (35.04)

982 (33.55)

330 (39.31)

0.026

 Now

545 (14.10)

433 (14.44)

112 (13.15)

0.735

Alcohol intake, n (%)

 Never

488 (10.48)

379 (10.34)

109 (10.88)

Ref

 Former

732 (15.24)

572 (15.48)

160 (14.57)

0.862

 Mild

1625 (48.59)

1223 (47.07)

402 (52.92)

0.344

Moderate

463 (14.56)

358 (14.79)

105 (13.88)

0.912

 Heavy

398 (11.13)

338 (12.32)

60 ( 7.74)

0.015

Hypertension, n (%)

 No

1549 (46.28)

1274 (49.29)

275 (37.68)

Ref

 Yes

2157 (53.72)

1596 (50.71)

561 (62.32)

 < 0.0001

Diabetes, n (%)

 No

3091 (87.65)

2405 (88.31)

686 (85.75)

Ref

 Yes

615 (12.35)

465 (11.69)

150 (14.25)

0.295

Cancer, n (%)

 No

3154 (83.75)

2485 (85.47)

669 (78.85)

Ref

 Yes

552 (16.25)

385 (14.53)

167 (21.15)

 < 0.0001

Physical activity (MET/week), mean (SD)

3103.84 (101.91)

3149.90 (116.79)

2972.47 (192.50)

0.42

Atherosclerosis, n (%)

 No

974 (24.99)

883 (30.07)

91 (10.51)

Ref

 Unknown

2728 (74.93)

1984 (69.85)

744 (89.43)

 < 0.0001

 Yes

4 (0.08)

3 (0.08)

1 (0.06)

0.328

TG (mg/dl), mean (SD)

123.50 (1.65)

122.10 (1.90)

127.51 (3.02)

0.12

TC (mg/dl), mean (SD)

201.47 (0.91)

202.39 (1.04)

198.84 (1.72)

0.07

HDL (mg/dl), mean (SD)

57.43 (0.48)

56.90 (0.55)

58.95 (0.75)

0.02

LDL (mg/dl), mean (SD)

119.33 (0.79)

121.07 (0.88)

114.39 (1.53)

 < 0.001