Figure 4 | Scientific Reports

Figure 4

From: Transcriptomic characterization of the human segmental endotoxin challenge model

Figure 4

Volcano plot for differential expression analysis results for (a) BAL and (b) biopsy samples, post LPS (BAL: n = 24, biopsy: n = 16) vs. post saline (BAL: n = 23, biopsy: n = 20) challenge. Differentially expressed genes are highlighted in red for upregulated genes (adjusted p-value ≤ 0.05, log2FC ≥ 1, BaseMean ≥ 2) and in blue for downregulated genes (adjusted p-value ≤ 0.05, log2FC ≤ − 1, BaseMean ≥ 2). The ten most significant genes are labelled with their official gene abbreviations according to ENSEMBL27. BAL bronchoalveolar lavage, LPS lipopolysaccharide, log2FC log twofold change.

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