Table 7 Developed methods in comparison with reported methods.
Method | Drug | Proposed methods | Reported methods | |||
|---|---|---|---|---|---|---|
UV method | MCR method | Spectrophotometric methods (10) | HPLC method (9) | HPTLC method (9) | ||
Linearity (μg mL1−) | BUP | 70–900 | 100–900 | 50–700 | 10.0–200.0 | 5.0–150.0 |
MEL | 20–120 | 20–120 | 1–10 | 1.0–100.0 | 1.0–25.0 | |
LOD (μg mL1−) | BUP | 13.2 | 22.77 | 8.86–13.64 | 3.198 | 0.48 |
MEL | 2.39 | 5.65 | 0.06–0.31 | 0.314 | 0.311 | |
Solvent | 0.3%SDS | 0.1N HCl* | Methanol* | Methanol* | ||
Analytical eco scale | 90 | 90 | 73 | 80 | ||
