Table 1 Pleiotropy and heterogeneity test of the MR analysis. T1D type 1 diabetes, SLE systemic lupus erythematosus, RA rheumatoid arthritis, MS multiple sclerosis, JIA juvenile idiopathic arthritis, CD celiac disease, PSC primary sclerosing cholangitis.

From: Exploring potential causal associations between autoimmune diseases and colorectal cancer using bidirectional Mendelian randomization

Exposure

Pleiotropy test

Heterogeneity test

MR-Egger

Inverse variance weighted

Intercept

SE

P

Q

Q_df

Q_pval

T1D

− 0.001

0.006

0.806

62.724

39

0.007

SLE

− 0.007

0.004

0.087

38.249

33

0.243

RA

0.000

0.003

0.862

52.023

42

0.138

Psoriasis

− 0.001

0.004

0.814

38.203

28

0.095

MS

0.000

0.004

0.945

56.693

36

0.015

JIA

− 0.003

0.012

0.797

8.555

6

0.200

CD

0.002

0.005

0.698

18.577

13

0.137

PSC

0.000

0.008

0.986

8.261

8

0.408

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