Table 1 Patient demographics and DWI findings.
Parameter | Probable sCJD (n = 56) |
|---|---|
Mean age (years) | 61.2 ± 9.9* |
Sex | |
Male | 26 (46%) |
Female | 30 (54%) |
Protein 14–3-3 | |
Negative | 9 (16%) |
Positive | 28 (50%) |
NA | 19 (34%) |
PRNP polymorphism | |
Negative | 23 (41%) |
Positive | 15 (27%) |
NA | 18 (32%) |
Cortex involvement on DWI | |
Negative | 1 (2%) |
Positive | 55 (98%) |
Deep gray matter involvement on DWI | |
Negative | 24 (43%) |
Positive | 32 (57%) |
Involved location (cortex) | |
Frontal lobe | 49 (88%) |
Parietal lobe | 50 (89%) |
Temporal lobe | 43 (77%) |
Occipital lobe | 35 (63%) |
Number of involved lobes | |
0–2 (minimal involvement) | 8 (14%) |
3–5 (moderate involvement) | 21 (38%) |
6–8 (extensive involvement) | 27 (48%) |
Involved location (deep gray matter) | |
Caudate nucleus | 11 (42%) |
Putamen | 8 (31%) |
Thalamus | 3 (12%) |
