Table 5 Stratification analysis in different subgroups.

From: Nonlinear relationship between gonadotropin total dose applied and live birth rates in non-PCOS patients: a retrospective cohort study

Stratification characteristics

N

LBR

P for interaction

Adjusted OR (95%Cl)

P value

Female age

 < 0.05

 ≤ 35

9756

0.92 (0.87, 0.97)

 < 0.001

 

 > 35

1888

1.06 (0.94, 1.19)

0.351

 

Infertility duration (year)

0.089

 ≤ 1

2239

1.06 (0.95, 1.18)

0.292

 

 > 1

9224

0.94 (0.89, 0.99)

 < 0.05

 

BMI (kg/m2)

0.247

 ≤ 24

7247

0.97 (0.92, 1.04)

0.407

 

 > 24

4248

0.94 (0.87, 1.01)

0.074

 

AFC

0.390

 ≤ 10

4242

1.00 (0.93, 1.09)

0.909

 

 > 10

5283

0.93 (0.86, 1.00)

0.056

 

Endometrium thickness on hCG trigger day (mm)

0.597

 ≤ 7

442

0.88 (0.70, 1.12)

0.308

 

 > 7

11,107

0.97 (0.92, 1.01)

0.157

 

Infertility type

0.322

 Primary infertility

6328

0.96 (0.90, 1.02)

0.167

 

 Secondary infertility

5317

0.96 (0.89, 1.03)

0.265

 

Stimulation protocol

0.094

 GnRH-agonist protocol

5515

0.86 (0.80, 0.93)

 < 0.001

 

 Prolonged GnRH-agonist protocol

2910

0.92 (0.84, 1.01)

0.086

 

 GnRH-antagonist protocol

1885

0.97 (0.85, 1.10)

0.629

 

 Data missing

1335

0.90 (0.78, 1.05)

0.186

 

Method of fertilization

0.200

 IVF

9208

0.97 (0.92, 1.02)

0.2233

 

 ICSI

2391

0.93 (0.83, 1.03)

0.1745

 

 IVF&ICSI

41

–

–

 
  1. The following factors, except the stratification factor itself, were adjusted in the multivariable analysis: female age, BMI, infertility duration, infertility type, endometrium thickness on hCG trigger day, embryo stage, and method of fertilization.
  2. BMI body mass index, AFC antral follicular count, Gn gonadotropin, P progesterone, GnRH gonadotropin releasing hormone, IVF in vitro fertilization, ICSI intracytoplasmic single sperm injection.
Back to article page