Figure 5

Homology model of the BmeTC. The 3D structure of BmeTC was modeled using AlphaFold2. The structure was constructed using the coordinates of SHC complexed with 2-azasqualene inhibitor [Protein Data Bank (PDB) code: 1UMP] as a template and visualized using PYMOL. Blue: 2-azasqualene; red: residues targeted in this study; green: initiation site.