Table 1 Ratio of products formed from substrate 2.

From: Analysis of vitamin D receptor binding affinities of enzymatically synthesized triterpenes including ambrein and unnatural onoceroids

 

3

5

6

9

10

11

12

Aa

WT

45.1

36.5

18.4

–

–

–

–

–

Y167A

1.6

20.8

41.9

21.6

–

4.8

3.0

6.3

Y257A

–

17.5

57.4

–

–

9.1

–

16.0

N302A

13.4

10.1

67.1

–

–

1.9

–

7.5

L596A

7.2

31.6

52.5

–

6.6

2.1

–

–

F600A

65.5

12.3

13.3

–

–

–

–

8.9

  1. aBecause A could not be isolated, its structure could not be determined.
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