Table 2 GWAS-identified SNPs and corresponding genes via eQTL search in cold hypersensitivity.

From: Exploratory study of cold hypersensitivity in Japanese women: genetic associations and somatic symptom burden

SNP

CHR

BP

A1

A2

MAF

P value

Odds ratio

SE

eGenes

rs750707

1

30,282,320

G

A

0.42

1.24E−06

1.56

0.09

–

rs1869201

1

215,173,014

G

A

0.42

2.04E−06

0.66

0.09

KCNK2

rs62295776

3

191,853,763

A

T

0.27

8.91E−06

0.64

0.10

–

rs10016576

4

91,484,515

G

C

0.48

5.07E−06

1.50

0.09

–

rs74513903

7

10,410,139

T

C

0.20

9.98E−06

0.62

0.11

–

rs2656514

7

42,777,914

G

A

0.30

8.35E−06

0.65

0.10

GLI3

rs12761019

10

7,788,209

A

G

0.11

5.10E−06

0.52

0.14

ITIH2, KIN

rs17098278

14

61,831,860

C

T

0.22

6.85E−06

0.61

0.11

–

rs10220484

14

99,457,631

C

T

0.31

6.49E−06

1.55

0.10

–

rs2876278

20

12,230,024

G

A

0.35

7.78E−06

1.51

0.09

–

rs4818919

21

45,849,864

G

A

0.15

8.09E−06

1.73

0.12

AP001062.7, TRPM2, MTND5P1, C21orf2

  1. SNP single nucleotide polymorphism, CHR chromosome, BP base-pair, GRCh37 genomic coordinate, A1 minor allele, A2 major allele, OR odds ratio for A1 allele, SE standard error of the OR, MAF minor allele frequency, eGenes expression Quantitative Trait Locus genes, are identified based on a Q-value threshold in the Genotype-Tissue Expression (GTEx) project database.
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