Table 3 Regression analysis of potential risk factors for increasing the preterm developmental defects of enamel score.

From: Natal factors affecting developmental defects of enamel in preterm infants: a prospective cohort study

T score (M + P score)

Descriptive analysis

Regression analysis

Independent variable

n

Average

SD

Median

IQR

P-value

B

95% CI

P-value

Prenatal risk factors

 Advanced maternal age

Yes

59

10.46

10.86

7.00

13.00

0.0795

3.5041

− 0.3978 to 7.4060

0.0778

No

43

6.95

8.14

4.00

10.00

Reference

  

 Maternal abortion history

Yes

27

11.07

12.51

7.00

14.00

0.6173

3.1241

− 1.2933 to 7.5415

0.1633

No

60

7.95

7.97

6.50

9.50

Reference

  

Neonatal risk factors

 Gestational age (weeks)

 < 28

43

14.09

13.31

10.00

13.00

0.0047*

6.4797

2.4966–10.4628

0.0017*

 ≥ 28

75

7.61

8.52

5.00

12.00

Reference

  

 Birth weight (g)

 < 1000

47

12.62

11.60

10.00

12.00

0.0100*

4.3917

0.3851–8.3982

0.0320*

 ≥ 1000

71

8.23

10.17

5.00

12.00

Reference

  

 Delivery mode

c-sec

97

10.42

11.05

7.00

13.00

0.2051

2.5227

− 7.8629 to 2.8175

0.3514

NVSD

20

7.90

10.63

3.00

9.50

Reference

  

 APGAR score 1 mina

 < 7

95

10.11

10.55

7.00

13.00

0.0029*

6.9386

0.7702–13.1070

0.0278*

 ≥ 7

12

3.17

5.70

0.00

3.50

Reference

  

 APGAR score 5 mina

 < 8

84

10.26

9.72

8.00

11.50

0.0005*

4.3489

− 0.4268 to 9.1245

0.0738

 ≥ 8

23

5.91

11.99

2.00

4.00

Reference

  

 Multiple pregnancy

Multiplet

44

9.66

12.42

6.00

12.00

0.2821

-0.5327

− 4.6975 to 3.6321

0.8005

singlet

73

10.19

10.09

8.00

13.00

Reference

  

Postnatal risk factors

 Medical complications

  Bronchopulmonary dysplasia

Yes

66

12.88

12.14

10.00

11.00

0.0001*

7.6496

3.9083 to 11.3910

 < 0.0001*

No

48

5.23

5.68

3.50

6.50

Reference

  

  Ricket

Yes

27

12.44

13.00

9.00

11.00

0.1591

3.6513

− 0.9505 to 8.2532

0.1187

No

87

8.79

9.68

7.00

11.00

Reference

  

  Intraventricular hemorrhage

Yes

40

12.88

12.60

9.00

13.00

0.0391*

4.9561

0.9168–8.9954

0.0166*

No

74

7.92

8.98

6.00

10.00

Reference

  

  Necrotizing enterocolitis

Yes

13

22.92

16.18

27.00

27.00

0.0022*

14.9726

9.4170–20.5282

 < 0.0001*

No

101

7.95

8.37

7.00

10.00

Reference

  

  Hyperbilirubinemia

Yes

73

8.44

10.04

6.00

11.00

0.1018

-3.3909

− 7.4633 to 0.6815

0.1018

No

41

11.83

11.36

10.00

11.00

Reference

  

  Intrauterine growth restriction

Yes

21

6.24

5.45

6.00

8.00

0.2111

-4.3397

− 9.4535 to 0.7742

0.0954

No

90

10.58

11.50

7.50

13.00

Reference

  

  Hypocalcemia

Yes

18

10.28

9.35

7.00

11.00

0.5090

0.7361

− 4.6864 to 6.1587

0.7884

No

96

9.54

10.87

7.00

11.50

Reference

  

  Sepsis

Yes

31

10.74

10.95

9.00

14.00

0.5882

1.4889

− 2.9476 to 5.9254

0.5074

No

83

9.25

10.52

7.00

11.00

Reference

  

 Parenteral feeding (month)a

 ≥ 1

28

12.14

11.28

9.00

10.00

0.0351*

4.3400

− 0.0891 to 8.7692

0.0547

 < 1

71

7.80

9.46

5.00

12.00

Reference

  

 Endotracheal intubation (month)a

 ≥ 1

23

13.43

13.12

9.00

10.00

0.0426*

5.0583

0.2779–9.8387

0.0383*

 < 1

85

8.38

9.36

6.00

12.00

Reference

  

 NICU admission (month)a

 ≥ 2

69

12.20

10.58

10.00

11.00

 < 0.0001*

7.3458

3.5820–11.1095

0.0002*

 < 2

42

4.86

7.35

2.00

7.00

Reference

  
  1. For descriptive analysis, the p-value was tested using the Wilcoxon rank-sum test. For logistic regression, the p-value was tested using a generalized linear model.
  2. C-sec cesarean section, NSVD normal spontaneous vaginal delivery, NICU neonatal intensive care unit.
  3. *p < 0.05 indicates statistical significance.
  4. aIndicates that the cutoff value was determined using the receiver operating characteristic (ROC) curve.