Table 1 Baseline characteristics of the study subjects.
Group | Age | Sex | RAASB | ISD | Pathologic classification | Glom N | Global sclerosis N (%) | Segmental sclerosis N (%) | Crescent N (%) | Diabetes | Hypertension | eGFR (mL/min/1.73 m2) | proteinuria (g/g or g/24Â h) | Electron microscopy | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Electron-dense deposit | GBM | Foot process effacement | ||||||||||||||
M0 | 30s | F | (−) | (−) | M0, E0, S0, T0, C0 | 12 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 110.3 | 0.34 | Small mesangial | (−) | Focal slight |
M0 | 50s | F | (+) | (−) | M0, E0, S1, T1, C0 | 25 | 2 (8%) | 1 (4%) | 0 (0%) | (−) | (+) | 86.9 | 0.51 | Small mesangial | (−) | (−) |
M0 | 30s | M | (−) | (−) | M0, E0, S0, T0, C0 | 25 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 110.3 | 0.14 | Small mesangial | (−) | Focal mild |
M0 | 20s | M | (−) | (−) | M0, E0, S0, T0, C0 | 27 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 134.70 | 0.18 | Small mesangial | (−) | (−) |
M1 | 30s | F | (−) | (−) | M1, E0, S1, T0, C0 | 15 | 2 (13%) | 3 (20%) | 0 (0%) | (−) | (−) | 105.8 | 2.44 | Small mesangial | (−) | Focal mild |
M1 | 20s | F | (−) | (−) | M1, E0, S1, T0, C0 | 59 | 8 (14%) | 2 (3%) | 0 (0%) | (−) | (−) | 136.2 | 3.13 | Moderate mesangial | (−) | Focal slight |
M1 | 50s | M | (+) | (−) | M1, E0, S1, T0, C0 | 34 | 7 (21%) | 4 (12%) | 0 (0%) | (−) | (+) | 67.50 | 1.66 | Small mesangial | Thickening | Focal mild |
M1 | 30s | F | (+) | (−) | M1, E1, S0, T0, C0 | 43 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 120.60 | 1.81 | Moderate mesangial, small subendothelial | (−) | Focal moderate |
Control | 20s | M | (−) | (−) | Banff: no positive findings | 75 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 112.6 | Not detected | Small mesangial | (−) | Focal mild |
Control | 30s | F | (−) | (−) | Banff: no positive findings | 76 | 8 (11%) | 0 (0%) | 0 (0%) | (−) | (−) | 113.2 | Not detected | (−) | (−) | Focal slight |
Control | 40s | M | (−) | (−) | Banff: no positive findings | 24 | 0 (0%) | 0 (0%) | 0 (0%) | (−) | (−) | 111.9 | Not detected | (−) | (−) | (−) |
Control | 50s | F | (−) | (−) | Banff: interstitial fibrosis/tubular atrophy grade 1 (ci1, ct1, i-IFTA2, t-IFTA1) | 42 | 3 (7%) | 0 (0%) | 0 (0%) | (−) | (−) | 90.2 | Not detected | (−) | (−) | (−) |
