Table 3 Top gene ontologies in each annotation results.
Comparison | Direction | Domain | Gene ontology terms | False discovery rate | Annotated gene lists |
|---|---|---|---|---|---|
M0/Control | Up | Biological process | GO:0072275 (metanephric glomerulus morphogenesis) | 0.004 | TCF21 |
Molecular function | GO:0050681 (nuclear androgen receptor binding) | 0.019 | TCF21 | ||
Cellular component | NA | NA | NA | ||
Down | Biological process | GO:0034097 (response to cytokine) |  < 0.001 | FOS, ZFP36, KLF4, DUSP1, EGR1, KLF2, JUNB | |
Molecular function | GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding) |  < 0.001 | FOS, KLF4, EGR1, KLF2, JUNB | ||
Cellular component | GO:0000785 (chromatin) | 0.002 | FOS, KLF4, EGR1, KLF2, JUNB | ||
M1/Control | Up | Biological process | GO:0048646 (anatomical structure formation involved in morphogenesis) |  < 0.001 | TPM1, CFH, FMNL3, CNBP, BMP2, MYOF, THBS1, MYH10, ATP5IF1, THY1, MYL9, THSD7A, TCF21, CD9, IGFBP7, PTPRM, SULF1, CDIPT, LRP2, DAG1, MACF1, ACTN1, ITGA3, ITGAV, ITGB1, ITGB3, TNFRSF21 |
Molecular function | GO:0050839 (cell adhesion) |  < 0.001 | THBS1, NDRG1, THY1, CD9, PTPRM, DSP, PARK7, PRDX1, MACF1, CD151, ACTN1, BCAM, ITGA3, ITGAV, ITGB1, ITGB3 | ||
Cellular component | GO:0009986 (cell surface) |  < 0.001 | SORT1, CFH, ATP5PF, BMP2, THBS1, ATP5IF1, THY1, CD9, BST2, SULF1, LRP2, DAG1, CD151, BCAM, ITGA3, APOE, ITGAV, ITGB1, ITGB3, ATP5F1A | ||
Down | Biological process | GO:0033993 (response to lipid) | 0.002 | EGR1, FOS, ZFP36, DUSP1, REN, CEBPB, NR4A1 | |
Molecular function | GO:0001216 (DNA-binding transcription activator activity) |  < 0.001 | EGR1, FOS, ATF3, CEBPB, NR4A1 | ||
Cellular component | GO:0005667 (transcription regulator complex) | 0.015 | FOS, ATF3, CEBPB, NR4A1 | ||
M1/M0 | Up | Biological process | GO:0001944 (vascular development) |  < 0.001 | COL4A1, HSPG2, FLNA, COL18A1, TCF4, GJA5, HEG1, CTNNB1, IGFBP7, RCAN1, ZFP36L1, ECM1, ENG, ITGB1, VCAM1, MSN |
Molecular function | GO:0005201 (extracellular matrix constituent) |  < 0.001 | COL4A1, HSPG2, COL18A1, IGFBP7, ECM1, ENG, BGN | ||
Cellular component | GO:0030312 (extracellular matrix) |  < 0.001 | COL4A1, S100A6, HSPG2, COL18A1, IGFBP7, ECM1, ITGB1, LRRC32, BGN | ||
Down | Biological process | NA | NA | NA | |
Molecular function | NA | NA | NA | ||
Cellular component | NA | NA | NA |
