Table 2 Effect of KMP and/or 5-FU on food and water intake.

From: Integrated blood and organ profile analysis to evaluate ameliorative effects of kaempferol on 5-fluorouracil-induced toxicity

Groups

Food consumption (g)

Water consumption (ml)

Initial (prior treatment phase starts)

Final (end of treatment phase)

Initial (prior treatment phase starts)

Final (end of treatment phase)

Mean ± SEM

Mean ± SEM

Mean ± SEM

Mean ± SEM

Control (0.9% saline)

26.8 ± 0.4

28.4 ± 0.5

22.8 ± 0.3

24.4 ± 0.4

Control (0.5% CMC)

27.1 ± 0.3

29.1 ± 0.3

22.3 ± 0.1

24.7 ± 0.3

DMH

11.6 ± 0.2

12.4 ± 0.2a

17.4 ± 0.2

22.2 ± 0.1a

DMH/5-FU

9.8 ± 0.1

11.6 ± 0.4a,b

15.9 ± 0.2

20.4 ± 0.3a,b

DMH/KMP

13.8 ± 0.2

21.6 ± 0.3a,b,c

18.1 ± 0.4

25.8 ± 0.4a,b,c

DMH/5-FU(HD)/KMP

10.8 ± 0.3

16.6 ± 0.4a,b,c,d

17.3 ± 0.3

24.4 ± 0.2 a,b,c

DMH/5-FU(LD)/KMP

12.8 ± 0.3

20.6 ± 0.4a,b,c

17.6 ± 0.4

22.9 ± 0.7 a,b,d

  1. The values are represented as Mean ± SEM for n = 6 animals/group.
  2. ap < 0.001w.r.t control group; bp < 0.001w.r.t DMH group, cp < 0.001w.r.t DMH/5-FU group; dp < 0.01w.r.t DMH/KMP group.
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