Table 3 Assay of GEM, and RSV raw materials and their combined synthetic tablets using the proposed method and comparison with the reported spectrophotometric method.

From: In-lab synthesized turn-off fluorescence sensor for estimation of Gemigliptin and Rosuvastatin polypill appraised by Spider diagram, AGREE and whiteness metrics

 

Parameters

Proposed method

Reference method

GEM

RSV

GEM

RSV

Raw materials

Mean % recovery ± SDa

100.66 ± 0.24

99.51 ± 0.38

100.28 ± 0.53

99.26 ± 0.79

RSD%

0.24

0.38

0.53

0.80

F-testb

0.21

0.23

 

t-testb

1.47

0.64

Synthetic Zemiro tablets

Mean % recovery ± SDa

98.83 ± 0.86

100.19 ± 0.64

99.77 ± 0.75

99.39 ± 0.94

RSD%

0.87

0.64

0.75

0.95

F-testb

1.25

0.47

  

t-testb

0.51

1.58

  
  1. aMean% recovery ± SD of five determinations.
  2. bThe tabulated values of F and t, at p = 0.05, are 6.39 and 1.86, respectively.
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