Table 3 GO enrichment analysis results of MRDEGs.

From: Identification of a novel macrophage-related prognostic signature in colorectal cancer

Ontology

ID

Description

GeneRatio

BgRatio

pvalue

p.adjust

qvalue

BP

GO:0050727

Regulation of inflammatory response

12/36

485/18,670

5.86e-11

1.22e-07

6.52e-08

BP

GO:0006869

Lipid transport

10/36

365/18,670

1.17e-09

1.22e-06

6.48e-07

BP

GO:0010876

Lipid localization

10/36

400/18,670

2.82e-09

1.96e-06

1.04e-06

BP

GO:0070372

Regulation of ERK1 and ERK2 cascade

9/36

300/18,670

4.08e-09

2.13e-06

1.13e-06

BP

GO:0070371

ERK1 and ERK2 cascade

9/36

317/18,670

6.59e-09

2.75e-06

1.46e-06

CC

GO:0070820

Tertiary granule

4/36

164/19,717

2.21e-04

0.028

0.020

CC

GO:0009897

External side of plasma membrane

5/36

393/19,717

6.95e-04

0.044

0.032

CC

GO:0034774

Secretory granule lumen

4/36

321/19,717

0.003

0.069

0.051

CC

GO:0042581

Specific granule

3/36

160/19,717

0.003

0.069

0.051

CC

GO:0060205

Cytoplasmic vesicle lumen

4/36

338/19,717

0.003

0.069

0.051

MF

GO:0005125

Cytokine activity

7/36

220/17,697

2.56e-07

3.16e-05

2.13e-05

MF

GO:0048018

Receptor ligand activity

9/36

482/17,697

3.75e-07

3.16e-05

2.13e-05

MF

GO:0042379

Chemokine receptor binding

4/36

66/17,697

9.50e-06

5.35e-04

3.60e-04

MF

GO:0008009

Chemokine activity

3/36

49/17,697

1.34e-04

0.006

0.004

MF

GO:0045236

CXCR chemokine receptor binding

2/36

11/17,697

2.19e-04

0.007

0.005

  1. MRDEGs macrophage-related differentially expressed genes, GO gene ontology, BP biological process, CC cellular component, MF molecular function.