Table 3 GO enrichment analysis results of MRDEGs.
From: Identification of a novel macrophage-related prognostic signature in colorectal cancer
Ontology | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue |
|---|---|---|---|---|---|---|---|
BP | GO:0050727 | Regulation of inflammatory response | 12/36 | 485/18,670 | 5.86e-11 | 1.22e-07 | 6.52e-08 |
BP | GO:0006869 | Lipid transport | 10/36 | 365/18,670 | 1.17e-09 | 1.22e-06 | 6.48e-07 |
BP | GO:0010876 | Lipid localization | 10/36 | 400/18,670 | 2.82e-09 | 1.96e-06 | 1.04e-06 |
BP | GO:0070372 | Regulation of ERK1 and ERK2 cascade | 9/36 | 300/18,670 | 4.08e-09 | 2.13e-06 | 1.13e-06 |
BP | GO:0070371 | ERK1 and ERK2 cascade | 9/36 | 317/18,670 | 6.59e-09 | 2.75e-06 | 1.46e-06 |
CC | GO:0070820 | Tertiary granule | 4/36 | 164/19,717 | 2.21e-04 | 0.028 | 0.020 |
CC | GO:0009897 | External side of plasma membrane | 5/36 | 393/19,717 | 6.95e-04 | 0.044 | 0.032 |
CC | GO:0034774 | Secretory granule lumen | 4/36 | 321/19,717 | 0.003 | 0.069 | 0.051 |
CC | GO:0042581 | Specific granule | 3/36 | 160/19,717 | 0.003 | 0.069 | 0.051 |
CC | GO:0060205 | Cytoplasmic vesicle lumen | 4/36 | 338/19,717 | 0.003 | 0.069 | 0.051 |
MF | GO:0005125 | Cytokine activity | 7/36 | 220/17,697 | 2.56e-07 | 3.16e-05 | 2.13e-05 |
MF | GO:0048018 | Receptor ligand activity | 9/36 | 482/17,697 | 3.75e-07 | 3.16e-05 | 2.13e-05 |
MF | GO:0042379 | Chemokine receptor binding | 4/36 | 66/17,697 | 9.50e-06 | 5.35e-04 | 3.60e-04 |
MF | GO:0008009 | Chemokine activity | 3/36 | 49/17,697 | 1.34e-04 | 0.006 | 0.004 |
MF | GO:0045236 | CXCR chemokine receptor binding | 2/36 | 11/17,697 | 2.19e-04 | 0.007 | 0.005 |