Table 4 Multivariable-adjusted glycemic profile and insulin resistance across tertiles of nutrient pattern scores.

From: Nutrient patterns in relation to insulin resistance and endothelial dysfunction in Iranian women

 

Tertiles of NP1 score

Tertiles of NP2 score

Tertiles of NP3 score

T1 (n = 127)

T2 (n = 119)

T3 (n = 122)

P

T1 (n = 117)

T2 (n = 123)

T3 (n = 128)

P

T1 (n = 121)

T2 (n = 121)

T3 (n = 126)

P

FBG (mg/dL)

Crude

82.6 ± 1.1

81.9 ± 1.2

83.0 ± 1.1

0.78

81.2 ± 0.9

82.5 ± 1.3

83.7 ± 1.1

0.32

83.0 ± 1.4

82.1 ± 0.9

82.4 ± 0.9

0.85

Model 1a

82.4 ± 1.3

82.1 ± 1.2

82.7 ± 1.4

0.95

80.8 ± 1.2

82.5 ± 1.2

83.8 ± 1.2

0.23

83.7 ± 1.3

81.7 ± 1.2

81.8 ± 1.3

0.52

Model 2b

83.0 ± 2.7

81.1 ± 2.3

82.9 ± 2.9

0.82

81.1 ± 2.4

84.7 ± 2.4

81.1 ± 2.4

0.49

81.6 ± 2.7

82.1 ± 2.3

83.3 ± 2.7

0.91

Model 3c

82.7 ± 2.7

81.0 ± 2.4

83.2 ± 2.9

0.80

80.7 ± 2.4

84.9 ± 2.4

81.2 ± 2.4

0.46

81.3 ± 2.7

82.1 ± 2.4

83.4 ± 2.7

0.88

Model 4d

82.5 ± 2.8

80.5 ± 2.5

83.4 ± 2.9

0.73

80.5 ± 2.5

85.7 ± 2.5

80.2 ± 2.5

0.26

80.9 ± 2.8

81.9 ± 2.4

83.5 ± 2.7

0.82

Insulin (mU/L)

Crude

9.7 ± 1.1

7.4 ± 0.5

8.4 ± 0.6

0.14

8.8 ± 1.2

9.0 ± 0.6

7.8 ± 0.4

0.56

9.1 ± 1.1

8.5 ± 0.6

7.9 ± 0.5

0.60

Model 1a

9.3 ± 0.9

7.2 ± 0.8

9.2 ± 0.9

0.15

8.9 ± 0.8

8.9 ± 0.8

7.9 ± 0.8

0.62

8.3 ± 0.9

8.4 ± 0.8

8.9 ± 0.9

0.90

Model 2b

10.6 ± 1.2

8.5 ± 1.1

7.1 ± 1.3

0.23

8.6 ± 1.1

10.7 ± 1.1

7.05 ± 1.1

0.08

7.5 ± 1.2

7.8 ± 1.0

11.0 ± 1.2

0.11

Model 3c

10.4 ± 1.2

8.4 ± 6.2

7.2 ± 1.3

0.28

8.4 ± 1.1

10.6 ± 1.1

7.0 ± 1.1

0.09

7.2 ± 1.2

7.8 ± 1.0

11.0 ± 1.2

0.10

Model 4d

10.4 ± 1.2

8.3 ± 1.1

7.3 ± 1.3

0.29

8.4 ± 1.1

10.8 ± 1.1

6.8 ± 1.1

0.06

7.2 ± 1.2

8.0 ± 1.1

10.7 ± 1.2

0.17

HOMA-IR

Crude

2.0 ± 0.2

1.5 ± 0.1

1.7 ± 0.1

0.19

1.8 ± 0.2

1.8 ± 0.1

1.6 ± 0.1

0.63

1.9 ± 0.2

1.7 ± 0.1

1.6 ± 0.1

0.57

Model 1a

1.9 ± 0.2

1.5 ± 0.1

1.9 ± 0.2

0.16

1.8 ± 0.1

1.8 ± 0.1

1.6 ± 0.1

0.66

1.7 ± 0.2

1.7 ± 0.1

1.8 ± 0.2

0.92

Model 2b

2.2 ± 0.2

1.7 ± 0.2

1.5 ± 0.2

0.25

1.8 ± 0.2

2.2 ± 0.2

1.3 ± 0.2

0.04

1.5 ± 0.2

1.6 ± 0.2

2.3 ± 0.2

0.12

Model 3c

2.1 ± 0.2

1.7 ± 0.2

1.5 ± 0.3

0.32

1.7 ± 0.2

2.2 ± 0.2

1.3 ± 0.2

0.04

1.4 ± 0.2

1.6 ± 0.2

2.3 ± 0.2

0.10

Model 4d

2.1 ± 0.2

1.6 ± 0.2

1.5 ± 0.3

0.33

1.7 ± 0.2

2.3 ± 0.2

1.3 ± 0.2

0.02

1.4 ± 0.2

1.6 ± 0.2

2.2 ± 0.2

0.16

HOMA-β

Crude

225.7 ± 65.5

129.7 ± 29.7

60.2 ± 76.6

0.15

228.8 ± 64.7

95.6 ± 77.7

101.8 ± 32.8

0.22

146.4 ± 37.6

66.7 ± 77.4

202.5 ± 60.4

0.28

Model 1a

232.6 ± 69.7

119.6 ± 63.3

51.5 ± 73.4

0.25

234.0 ± 65.3

78.5 ± 63.0

102.9 ± 61.8

0.18

85.6 ± 70.6

54.5 ± 64.1

259.4 ± 69.8

0.09

Model 2b

388.1 ± 181.7

181.9 ± 158.5

− 96.6 ± 192.8

0.27

288.3 ± 162.3

− 68.8 ± 161.5

261.1 ± 162.5

0.24

44.1 ± 175.7

− 101.7 ± 154.9

542.0 ± 176

0.03

Model 3c

387.2 ± 184.5

162.3 ± 159.6

− 71.4 ± 194.5

0.32

254.7 ± 165.9

− 49.6 ± 165.1

267.0 ± 163.3

0.32

57.4 ± 178.5

− 116.2 ± 155.4

540.0 ± 176.3

0.02

Model 4d

407.2 ± 183.3

144.9 ± 162.6

− 72.3 ± 192.8

0.27

254.4 ± 167.8

10.3 ± 167.8

213.9 ± 166.5

0.56

48.7 ± 179.8

− 107.8 ± 157.5

531.3 ± 176.2

0.03

QUICKY

Crude

0.37 ± 0.005

0.37 ± 0.004

0.37 ± 0.004

0.59

0.38 ± 0.005

0.37 ± 0.004

0.37 ± 0.004

0.22

0.37 ± 0.005

0.37 ± 0.004

0.37 ± 0.003

0.73

Model 1a

0.37 ± 0.005

0.37 ± 0.005

0.37 ± 0.006

0.63

0.38 ± 0.005

0.37 ± 0.005

0.37 ± 0.005

0.21

0.37 ± 0.005

0.37 ± 0.005

0.37 ± 0.005

0.73

Model 2b

0.36 ± 0.01

0.37 ± 0.009

0.38 ± 0.01

0.54

0.38 ± 0.009

0.36 ± 0.009

0.37 ± 0.009

0.30

0.38 ± 0.01

0.38 ± 0.009

0.36 ± 0.01

0.21

Model 3c

0.37 ± 0.01

0.37 ± 0.009

0.38 ± 0.01

0.62

0.38 ± 0.009

0.36 ± 0.009

0.37 ± 0.009

0.24

0.38 ± 0.01

0.38 ± 0.009

0.36 ± 0.01

0.20

Model 4d

0.37 ± 0.01

0.37 ± 0.009

0.37 ± 0.01

0.69

0.38 ± 0.009

0.36 ± 0.009

0.38 ± 0.009

0.09

0.38 ± 0.01

0.38 ± 0.009

0.36 ± 0.01

0.19

  1. All values are means ± SE. P were obtained from analysis of covariance (ANCOVA). Q quartile, FBG fasting blood glucose, HOMA-IR homeostatic model assessment of insulin resistance, HOMA-β homeostatic model assessment of beta-cell function, QUICKI quantitative insulin sensitivity check index.
  2. aModel 1: Adjusted for age and energy intake.
  3. bModel 2: Further adjusted for physical activity (MET-h/wk), current corticoid steroids use (yes or no), current OCP use (yes or no), marital status (categorical), menopausal status (yes or no), systolic blood pressure, diastolic blood pressure, and socioeconomic status (categorical).
  4. cModel 3: Further adjusted for BMI.
  5. dModel 4: Additionally adjusted for markers of endothelial function (E-selectin, sICAM-1, and sVCAM-1).
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