Figure 6 | Scientific Reports

Figure 6

From: Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain

Figure 6

Control experiment demonstrating no significant effects on contraction following acute gene transfer of β-MyHC to β-MyHC dominant hiPSC-CMs. (A) Schematic of Ad β-MyHC construct. (B) Significant induction of β-MyHC mRNA upon gene transfer to hiPSC-CMs. *P < 0.01. (D–G) Summary data showing no significant effects of β-MyHC gene transfer on hiPSC-CMs contraction and kinetics. NS not significant.

Back to article page