Table 1 Information on 9 genotypes of E25 relying on full-length VP1 sequences.

From: Genotype F of Echovirus 25 with multiple recombination pattern have been persistently and extensively circulating in Chinese mainland

Genotype

Number of sequences

Isolated country

Isolated year

Distance to external clusters

Intra-cluster distances

MCMC (BEAST)

Nucleotide

Amino acid

(Nucleotide)

Substitution rate (10-3) (95%HPD)

tMRCA (95% HPD)

ALL

113

USA, India, Australia, France, China, Germany

1957–2018

NA

NA

NA

6.08 (5.10–7.16)

1923 (1901–1944)

A

1

USA

1957

0.233–0.247

0.047–0.070

NA

NA

NA

B

1

Australia

1995

0.184–0.242

0.036–0.053

NA

NA

NA

C

1

China

1998

0.182–0.236

0.031–0.058

NA

NA

NA

D

22

USA, India, Australia, France

2000–2012

0.158–0.247

0.039–0.070

0.11

NA

NA)

E

6

China, Germany, Australia

2003–2010

0.182–0.241

0.031–0.055

0.03

NA

NA

F

68

China, France, Australia, USA

2003–2018

0.157–0.236

0.029–0.061

0.08

6.44 (5.53–7.34)

1993 (1989–1996)

G

5

Australia, France, USA

2006–2017

0.158–0.233

0.037–0.066

0.11

NA

NA

H

8

India, China

2008–2017

0.157–0.236

0.030–0.069

0.07

NA

NA

I

1

USA

2016

0.170–0.241

0.029–0.058

NA

NA

NA