Table 5 Independent predictor of factors associated with premature coronary artery disease.

From: Coronary risk factor profiles according to different age categories in premature coronary artery disease patients who have undergone percutaneous coronary intervention

Parameters

A

B

C

D

Adjusted ORa (95%CI)

p-value*

Adjusted ORa (95%CI)

p-value*

Adjusted ORa (95%CI)

p-value*

Adjusted ORa (95%CI)

p-value*

Male

1.522 (1.232, 1.881)

 < 0.001

NS

NS

NS

NS

NS

NS

Female

NS

NS

1.832 (1.635, 2.053)

 < 0.001

1.764 (1.605, 1.939)

 < 0.001

3.994 (3.630, 4.395)

 < 0.001

Malay

1.129 (1.010, 1.263)

0.033

1.149 (1.063, 1.241)

 < 0.001

1.160 (1.087, 1.239)

 < 0.001

1.156 (1.083, 1.234)

 < 0.001

Current/former smoker

1.799 (1.579, 2.049)

 < 0.001

1.697 (1.550, 1.858)

 < 0.001

1.722 (1.599, 1.853)

 < 0.001

1.731 (1.607, 1.863)

 < 0.001

Obesity

1.799 (1.597, 2.026)

 < 0.001

1.899 (1.749, 2.063)

 < 0.001

1.838 (1.717, 1.966)

 < 0.001

1.835 (1.715, 1.963)

 < 0.001

Hypertension

0.493 (0.441, 0.550)

 < 0.001

0.524 (0.483, 0.569)

 < 0.001

0.565 (0.525, 0.608)

 < 0.001

0.571 (0.530, 0.615)

 < 0.001

Diabetes mellitus

0.655 (0.586, 0.732)

 < 0.001

0.810 (0.750, 0.875)

 < 0.001

0.861 (0.807, 0.919)

 < 0.001

0.871 (0.816, 0.930)

 < 0.001

Personal history of MI

1.627 (1.459, 1.814)

 < 0.001

1.431 (1.327, 1.542)

 < 0.001

1.366 (1.283, 1.456)

 < 0.001

1.368 (1.283, 1.457)

 < 0.001

Cerebrovascular disease

NS

NS

0.604 (0.451, 0.808)

0.001

0.683 (0.547, 0.853)

0.001

0.673 (0.540, 0.838)

 < 0.001

Peripheral vascular disease

NS

NS

NS

NS

0.596 (0.392, 0.909)

0.016

0.580 (0.384, 0.877)

0.010

Chronic kidney disease

0.494 (0.349, 0.698)

 < 0.001

0.622 (0.514, 0.752)

 < 0.001

0.803 (0.698, 0.924)

0.002

0.809 (0.704, 0.929)

0.003

Family history of PCAD

1.637 (1.453, 1.845)

 < 0.001

1.513 (1.385, 1.652)

 < 0.001

1.581 (1.461, 1.710)

 < 0.001

1.607 (1.484, 1.739)

 < 0.001

Total cholesterol

1.236 (1.188, 1.286)

 < 0.001

1.221 (1.184, 1.258)

 < 0.001

1.209 (1.176, 1.243)

 < 0.001

1.224 (1.190, 1.258)

 < 0.001

 

Hosmer and Lemeshow goodness-of-fit test, p-value: 0.553; Percentage prediction: 90.7%

Hosmer and Lemeshow goodness-of-fit test, p-value: 0.164; Percentage prediction: 78.1%

Hosmer and Lemeshow goodness-of-fit test, p-value: 0.825; Percentage prediction: 64.4%

Hosmer and Lemeshow goodness-of-fit test, p-value: 0.104; Percentage prediction: 64.7%

  1. A: < 45 years, B: Males: < 50 years; Females: < 55 years, C: Males: < 55 years; Females: < 60 years and D: Males: < 55 years; Females: < 65 years old.
  2. OR odds ratio, CI confidence interval, PCAD premature coronary artery disease.
  3. *Statistically significant at ɑ = 0.05. Model is fit, model assumptions are met and no multicollinearity problems.
  4. aStatistical test: Multiple Logistic Regression.
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