Table 2 Univariate Analysis of Outcomes Stratified by Sex-Specific HDL Quartiles.

From: Association between HDL levels and stroke outcomes in the Arab population

Sex-specific HDL cut-offs

Low HDL (n = 658)

Low-Normal HDL (n = 722)

High-Normal HDL (n = 309)

High HDL (n = 400)

p-value

M: ≤ 0.80 F: ≤ 1.00

M: 0.80–1.00 F: 1.00–1.30

M: 1.00–1.12 F: 1.30–1.60

M: > 1.12 F: > 1.60

Inpatient outcomes

 LOS, d, median [IQR]

4 [3–7]

4 [2–6]

4 [2–7]

4 [2–6]

0.045*

 In-hospital mortality, n (%)

11 (1.7)

8 (1.1)

5 (1.6)

10 (2.5)

0.372

 Thrombolysis, n (%)

76 (11.6)

67 (9.3)

36 (11.7)

34 (8.5)

0.267

 Thrombectomy, n (%)

34 (5.2)

19 (2.6)

7 (2.3)

11 (2.8)

0.026*

 ICU admission, n (%)

29 (4.4)

28 (3.9)

12 (3.9)

18 (4.5)

0.936

 In-hospital complications, n (%)

67 (10.2)

63 (8.7)

24 (7.8)

36 (9.0)

0.632

Post-discharge long-term outcomes

 1-y stroke recurrence, n (%)

36 (6.1)

19 (2.9)

8 (3.0)

10 (2.9)

0.014*

 mRS at 90 days, median [IQR]

2 [0–3]

1 [0–3]

1 [0–3]

1 [0–3]

0.076

 90-day mortality, n (%)

26 (4.8)

26 (4.4)

11 (4.4)

6 (1.9)

0.209

 1-y mortality, n (%)

35 (5.9)

38 (5.9)

17 (6.3)

9 (2.6)

0.094

 1-y post-stroke MACE, n (%)

76 (11.7)

61 (8.5)

29 (9.5)

24 (6.2)

0.021*

 1-y post-stroke MI, n (%)

7 (1.2)

3 (0.5)

1 (0.4)

Nil

0.116

 1-y post-stroke cardiac revascularization, n (%)

4 (0.7)

4 (0.6)

3 (1.1)

2 (0.6)

0.844

  1. HDL high-density lipoprotein, LOS length of stay, d days, y year, IQR interquartile range, ICU intensive care unit, MRS modified Rankin Scale, MACE major adverse cardiac event, MI myocardial infarction, M males, F females.
  2. Long-term outcomes and in-hospital LOS were assessed among survivors of index hospital admission.