Figure 5
From: Vascularised cardiac spheroids-on-a-chip for testing the toxicity of therapeutics
Cytoskeletal and junction markers further confirm the structure and integrity of the system. (A) α-actinin (cyan, first column) and F-actin (yellow, second column) formed a striated pattern. Non-muscle myosin II (magenta, third column). These are z-projections of confocal images. Fifth column is a high resolution single plane. (B) β-catenin (cyan, first column) and N-cadherin (yellow, second column) are expressed in cell–cell junctions. CD31 (magenta, third column) stains the vasculature. Scale bar is 100 µm.
