Figure 8

Species network post VagiBIOM treatment (Day 28). Blue nodes represent bacterial species, pink nodes represent clinical parameters, and edges represent a connection between them. Green and red lines represent positive and negative associations, respectively. All associations are significant (p < 0.05). *Continuous lines represent correlation coefficients ≥ 0.75 to 1 for positive associations and − 0.75 to − 1 for negative associations. Dash-dotted lines represent a correlation coefficient ≥ 0.65–0.75 for a positive association and ≥ − 0.65 to − 0.75 for a negative association. The dotted lines represent a correlation coefficient < 0.65 for a positive association < − 0.65 for a negative association. Abbreviations BMI, Body Mass Index; VAS, Visual analog scale; VHI, Vaginal health index.