Table 4 Safety profile of rituximab (RTX) in Thai MS and NMOSD patients.

From: Efficacy and safety of rituximab in multiple sclerosis and neuromyelitis optica spectrum disorder

Adverse drug reactions

Total patients (n = 75)

Experienced adverse drug reactions, n (%)

33 (44.0)

 Infusion reactions*

22 (29.3)

 Infection†

7 (9.3)

 Leukopenia, white blood cell count < 3000/μL

4 (5.3)

 Lymphopenia, absolute lymphocyte count < 1000/μL

5 (6.7)

 Others‡

2 (2.7)

  1. RTX Rituximab.
  2. *Infusion reactions included fever (n = 5), rash (n = 4), chill (n = 4), hypotension (n = 2), headache (n = 2), hypertension (n = 1), chest tightness (n = 1), palpitation (n = 1), rhinorrhea (n = 1), nausea (n = 1), hand numbness (n = 1), burning sensation both feet (n = 1).
  3. †Infection included upper respiratory tract infection (n = 1), pneumonia (n = 1), urinary tract infection (n = 3), zoster infection (n = 1), acute gastroenteritis (n = 1).
  4. ‡Others were myalgia (n = 1) and arthralgia (n = 1).
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