Figure 5
From: Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study

Comparison of voxelwise values of Ktrans and vp obtained using the LEGATOSLDHS and LEGATOSDICE reconstruction methods. Values shown for all tumour voxels in the schwannoma (panel A, N = 40,116 voxels), chondrosarcoma (panel B, N = 8079 voxels) and chordoma (panel C, N = 3034 voxels) tumour subgroup along with a pooled analysis of tumour voxels across all three tumour groups (panel D, N = 51,229 voxels). Within each panel the voxelwise correlation between LEGATOSLDHS and LEGATOSDICE derived estimates for Ktrans (top left) and vp are shown (bottom left). The correlation between the full dose LEGATOSDICE derived estimates and the voxelwise difference between LEGATOSLDHS and LEGATOSDICE estimates is also shown (top and bottom right), along with the median bias or voxelwise difference (median % difference relative to LEGATOSFDHS estimate) for each of the LEGATOSLDHS derived parameters. The correlation results are reported using Pearson’s product moment correlation coefficient (r). Voxels with an SFE value > 0.5 and voxel values > 99% centile are excluded from the scatterplots shown.