Table 2 Causal effect from alcohol consumption to endometrial cancer risk factors.

From: The causal effects of genetically predicted alcohol consumption on endometrial cancer risk from a Mendelian randomization study

Outcomes

GWAS ID

Number of SNPs

Method

Causal effect

95% CI

P value

Estradiol

ebi-a-GCST90012105

55

Weighted median

1.03

1.00–1.06

0.034

Human chorionic gonadotropin

prot-a-688

57

IVW(MRE)

0.55

0.32–0.95

0.031

Insulin-like growth factor 1

ukb-d-30770_irnt

45

IVW(MRE)

0.88

0.80–0.98

0.017

Sex hormone-binding globulin levels

ebi-a-GCST90012111

57

IVW(FE)

1.02

0.99–1.04

0.207

Total Testosterone

ieu-b-4864

47

IVW(MRE)

1.08

0.99–1.17

0.680

Membrane-associated progesterone receptor component 2

prot-a-2260

57

IVW(MRE)

0.77

0.45–1.30

0.327

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