Table 1 Plasma lipid profile (mg/dl), adipocyte hormones (µg/L), nitric oxide (µmol/ml) levels and blood pressure (mmHg) of obese rats treated with zinc oxide nanoparticles.

From: Author Correction: Zinc nanoparticles ameliorated obesity-induced cardiovascular disease: role of metabolic syndrome and iron overload

Parameter

Treatment

Control

Obese

O + ZnONPs 5 mg/kg

O + ZnONPs 10 mg/kg

Cholesterol

90.63 ± 2.76

197.60 ± 4.97*

131.50 ± 2.77*@

87.13 ± 6.58@#

Triglycerides

66.88 ± 1.66

231.50 ± 13.63*

200.50 ± 14.47*

168.60 ± 12.86*@

HDL

37.57 ± 2.28

12.00 ± 0.54*

28.13 ± 2.35*@

40.00 ± 2.41@#

LDL

21.88 ± 1.27

87.38 ± 1.90*

43.63 ± 2.21*@

25.25 ± 0.88@#

Atherogenic index

0.26 ± 0.02

1.31 ± 0.03*

0.87 ± 0.02*@

0.66 ± 0.04*@#

Leptin

1.87 ± 0.15

3.11 ± 0.15*

2.19 ± 0.25*@

1.94 ± 0.19@#

Adiponectin

196 ± 10.31

51.13 ± 1.49*

151.88 ± 8.33*@

188.13 ± 8.80@#

Nitric oxide

40.80 ± 1.16

17.88 ± 0.78*

26.00 ± 1.05*

38.50 ± 1.68@#

Systolic BP

117.87 ± 2.13

145.76 ± 2.95*

130.38 ± 1.06*@

121.62 ± 1.89 @

Diastolic BP

81.13 ± 1.62

102.50 ± 2.60*

88.38 ± 1.44@

80.75 ± 2.23@

  1. Each value represents the mean of 8 animals ± SE. Statistical analysis was performed using one-way ANOVA followed by Tukey–Kramer multiple comparisons test (*vs control group, @vs obese group and #vs ZnONPs 5 mg/kg) at p < 0.05. O: Obese.
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