Figure 1

Proliferating marker Ki-67 is higher on MUA (A-B) in comparison with LUA (C-D), IUA (E–F), CAM (G-H) and DF (I) samples. The markings were predominantly nuclear in the neoplastic cell parenchyma. Scales: 20 µm and 100 µm. Comparison of Ki-67 immunoexpression between the samples of MUA, LUA, IUA, CAM and DF, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05 (J). In figures B and H the immunostaining is observed mainly in the tall columnar cells on the periphery of the tumor islands (arrow). In figures D and F a weak staining is observed in most neoplastic cells (arrows).