Figure 2

Apoptosis marker Caspase-3 is lower in MUA (A, B) than in LUA (C, D), IUA (E, F), and CAM (G, H), except for DF (I). For LUA (C, D), IUA (E, F) and CAM (G, H), Capase-3 is higher than DF (I). The markings were weakly diffused into the cytoplasm in the parenchyma of neoplastic cells. Scales: 20 µm and 100 µm. Comparison of the immunoexpression of Caspase-3 between the samples of MUA, LUA, IUA, CAM and DF, ***p < 0.0001, **p < 0.001, *p < 0.05 (J). In figure B, immunostaining is barely observed in the tall columnar cells at the periphery of the tumor islands (arrow). In figures E and F, strong staining is observed in the many of neoplastic cells (arrows).