Figure 7

Remodelin inhibits the proliferation of OS cells by suppressing the expression of ESR2, IGF1 and MAPK1. (A) CCK-8 assay for the determination of Remodelin toxicity to OS cells. (B-F) The mRNA relative expression of ESR2, FGFR2, IGF1, MAPK1, CASP3. The data are presented as the mean ± SD of six independent experiments.*P < 0.05, **P < 0.01, ***P < 0.001.