Table 1 Baseline characteristics of the study population. ECOG Eastern Cooperative Oncology Group.

From: Risk-adapted locoregional radiotherapy strategies based on a prognostic nomogram for de novo metastatic nasopharyngeal carcinoma patients treated with chemoimmunotherapy

Characteristic

LRRT, n (%)

Without-LRRT, n (%)

P

Age (year)

1.000

 < 50

35 (50.7)

11 (52.4)

 

 ≥ 50

34 (49.3)

10 (47.6)

 

Gender

1.000

 Male

56 (81.2)

17 (81.0)

 

 Female

13 (18.8)

4 (19.0)

 

ECOG score

0.233

 0

0 (0)

1 (4.8)

 

 1

69 (100)

20 (95.2)

 

T stage

0.771

 T1-2

17 (24.6)

4 (19.0)

 

 T3-4

52 (75.4)

17 (81.0)

 

N stage

0.506

 N0-1

12 (17.4)

2 (9.5)

 

 N2-3

57 (82.6)

19 (90.5)

 

Pre-treatment EBV DNA

0.121

 < 66,600

47 (68.1)

10 (47.6)

 

 ≥ 66,600

22 (31.9)

11 (52.4)

 

Multiple organ metastasis

0.012

 No

42 (60.9)

6 (28.6)

 

 Yes

27 (39.1)

15 (71.4)

 

No. of metastatic lesions

0.177

 Single

14 (20.3)

1 (4.8)

 

 Multiple

55 (79.7)

20 (95.2)

 

Liver metastases

0.006

 No

47 (68.1)

7 (33.3)

 

 Yes

22 (31.9)

14 (66.7)

 

Bone metastases

0.430

 No

24 (34.8)

5 (23.8)

 

 Yes

45 (65.2)

16 (76.2)

 

Lung metastases

0.792

 No

47 (68.1)

13 (61.9)

 

 Yes

22 (31.9)

8 (38.1)

 

Lactate dehydrogenase (U/L)

0.036

 < 250

44 (67.7)

8 (40.0)

 

 ≥ 250

21 (32.3)

12 (60.0)

 

Cycle of first-line chemotherapy

0.202

 < 6

24 (34.8)

11 (52.4)

 

 ≥ 6

45 (65.2)

10 (47.6)

 

Cycle of first-line immune therapy

0.040

 < 8

37 (53.6)

17 (81.0)

 

 ≥ 8

32 (46.4)

4 (19.0)

 

Local treatment to metastasis

0.005

 No

44 (63.8)

20 (95.2)

 

 Yes

25 (36.2)

1 (4.8)