Figure 4

Correlations between ictal ICA source localization on the first SEEG and epileptogenicity values estimated across the two successive SEEG explorations in Patient 2. (A) Ictal ICA source localization (heatmap) (SLoreta map threshold = 50%) of the main component of SEEG1 and the maximal EI values (green spheres) projected on the patient’s brain mesh with SEEG electrodes of the first (left) and the second (right) implantations. Source localization of the IC92 is in the dysplastic right precentral sulcus and matches with the maximal EI values on the SEEG2 (electrode OC). (B) Patient’s axial and coronal MRI views showing ICA source localization of SEEG1 (left), the EI values of SEEG2 (represented on the respective contacts according to a color scale from red, maximal epileptogenicity, to green, no epileptogenicity), with the right insular resection performed after SEEG1 visible on the coronal slice (middle), and the resection of the perilesional opercular cortex after SEEG2 (right). The peak of the IC92 matches with the bottom of the dysplastic sulcus (yellow arrows) showing maximal epileptogenicity on SEEG2 and disconnected by the 2nd resection (removal could not be achieved due to the technical issues).