Table 2 Surgical outcomes of the PP population (n = 141).

From: Efficacy of neoadjuvant immunochemotherapy and survival surrogate analysis of neoadjuvant treatment in IB–IIIB lung squamous cell carcinoma

 

Total, n = 141

Chemotherapy, n = 48

Immunochemotherapy, n = 93

P-value

Time from first treatment to surgery, median (IQR), day

79.2 (52.0–100.0)

75.4 (51.0–111.0)

81.2 (51.5–101.5)

0.085

Surgical approach, n (%)

   

0.527

 Open

92 (65.2)

34 (70.8)

58 (62.4)

 

 VATS

25 (17.7)

8 (16.7)

17 (18.3)

 

 RATS

3 (2.1)

0 (0.0)

3 (3.2)

 

 VATS-open

21 (14.9)

6 (12.5)

15 (16.1)

 

Operation method, n (%)

   

0.547

 Wedge resection

3 (2.1)

1 (2.1)

2 (2.2)

 

 Segmental resection

2 (1.4)

0 (0.0)

2 (2.2)

 

 Lobectomy

74 (52.5)

30 (62.5)

44 (47.3)

 

 Sleeve lobectomy

42 (29.8)

11 (22.9)

31 (33.3)

 

 Exploratory thoracotomy

5 (3.5)

1 (2.1)

4 (4.3)

 

 Total pneumonectomy

15 (10.6)

5 (10.4)

10 (10.8)

 

Operation time, median (IQR), min

165.6 (116.0–211.0)

169.6 (107.0–154.0)

163.6 (109.3–195.8)

0.581

Estimated blood loss, median (IQR), mL

102.7 (30.0–100.0)

115.9 (50.0–200.0)

96.1 (20.0–100.0)

0.880

Number of lymph node dissections during surgery, median (IQR), n

17.2 (10.0–21.5)

14.6 (9.0–18.0)

18.5 (11.0–24.0)

0.141

Surgical margin, n (%)

   

0.217

 R0 resection

130 (92.2)

42 (87.5)

88 (94.6)

 

 R1 resection

8 (5.7)

5 (10.4)

3 (3.2)

 

 R2 resection

3 (2.1)

1 (2.1)

2 (2.2)

 

Length of hospital stay, median (IQR), day

13.8 (9.0–17.8)

15.7 (11.0–19.0)

12.8 (8.0–16.0)

0.320

Postoperative complication, n (%)

    

 Overall complication

64 (45.4)

19 (39.6)

45 (48.4)

0.372

 Hydropneumothorax

23 (16.3)

13 (27.1)

10 (10.8)

0.013

 Hydrothorax

33 (23.4)

6 (12.5)

27 (29.0)

0.028

 Pneumothorax

7 (5.0)

0 (0.0)

7 (7.1)

0.051

 Chylothorax

1 (0.7)

0 (0.0)

1 (1.0)

0.471

 Bronchial obstruction

1 (0.7)

0 (0.0)

1 (1.0)

0.471

ypTNM stage, n (%)

   

0.058

 0

49 (34.8)

10 (20.8)

39 (41.9)

 

 IA

27 (19.1)

8 (16.7)

19 (20.4)

 

 IB

8 (5.7)

4 (8.3)

4 (4.3)

 

 IIA

3 (2.1)

1 (2.1)

2 (2.2)

 

 IIB

26 (18.4)

9 (18.8)

17 (18.3)

 

 IIIA

22 (15.6)

12 (25.0)

10 (10.8)

 

 IIIB

6 (4.3)

4 (8.3)

2 (2.2)

 
  1. PP, postoperative; IQR, interquartile range; VATS, video-assisted thoracoscopic surgery; RATS, robot-assisted thoracoscopic surgery.
  2. Significant values are in bold.
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