Table 3 Changes of clinical stage of the ITT population (n = 231) before (cStage) and after (ycStage) neoadjuvant treatment.

From: Efficacy of neoadjuvant immunochemotherapy and survival surrogate analysis of neoadjuvant treatment in IB–IIIB lung squamous cell carcinoma

Characteristic

Chemotherapy

Immunochemotherapy

cStage,

ycStage,

P-value

cStage,

ycStage,

P-value

n = 78

n = 78

n = 153

n = 153

T stage, n (%)

  

0.009

  

 < 0.001

 T0

0 (0.0)

1 (1.3)

 

0 (0.0)

0 (0.0)

 

 T1a

0 (0.0)

1 (1.3)

 

0 (0.0)

13 (8.5)

 

 T1b

3 (3.8)

13 (16.7)

 

6 (3.9)

38 (24.8)

 

 T1c

11 (14.1)

23 (29.5)

 

15 (9.8)

42 (27.5)

 

 T2a

14 (17.9)

12 (15.4)

 

31 (20.3)

23 (15.0)

 

 T2b

14 (17.9)

8 (10.3)

 

35 (22.9)

19 (12.4)

 

 T3

21 (26.9)

12 (15.4)

 

36 (23.5)

13 (8.5)

 

 T4

15 (19.2)

8 (10.3)

 

30 (19.6)

5 (3.3)

 

N stage, n (%)

  

0.856

  

0.563

 N0

3 (3.8)

5 (6.4)

 

8 (5.2)

11 (7.2)

 

 N1

12 (15.4)

13 (16.7)

 

26 (17.0)

33 (21.6)

 

 N2

60 (76.9)

58 (74.4)

 

117 (76.5)

106 (69.3)

 

 N3

3 (3.8)

2 (2.6)

 

2 (1.3)

3 (2.0)

 

Stage, n (%)

  

0.046

  

 < 0.001

 0

0 (0.0)

1 (1.3)

 

0 (0.0)

0 (0.0)

 

 IA

0 (0.0)

4 (5.1)

 

0 (0.0)

5 (3.3)

 

 IB

1 (1.3)

0 (0.0)

 

4 (2.6)

3 (2.0)

 

 IC

0 (0.0)

0 (0.0)

 

0 (0.0)

0 (0.0)

 

 IIA

1 (1.3)

0 (0.0)

 

2 (1.3)

2 (1.3)

 

 IIB

9 (11.5)

11 (14.1)

 

17 (11.1)

33 (21.6)

 

 IIIA

32 (41.0)

42 (53.8)

 

75 (49.0)

91 (59.5)

 

 IIIB

35 (44.9)

19 (24.4)

 

55 (35.9)

19 (12.4)

 

 IVA

0 (0.0)

1 (1.3)

 

0 (0.0)

0 (0.0)

 
  1. ITT, intention-to-treat.
  2. Significant values are in bold.