Table 3 Association between early changes in laboratory indexes and treatment modalities in DC patients with significant coagulation.

From: Efficacy of fresh frozen plasma transfusion in decompensated cirrhosis patients with coagulopathy admitted to ICU: a retrospective cohort study from MIMIC-IV database

Indexes

FFP transfusion

Day

Day × FFP transfusion

PT (sec)

− 2.38 (− 4.62, − 0.14)*

− 0.22 (− 0.47, 0.03)

0.30 (− 0.02, 0.63)

INR

− 0.16 (− 0.31, 0.01)*

− 0.02 (− 0.03, − 0.01)*

0.01 (0.004, 0.02)*

APTT (sec)

− 4.13(− 7.13, − 1.13)*

− 0.58 (− 0.78, − 0.38)*

0.61 (0.36, 0.87)*

AST/ALT

0.07 (− 0.16, 0.29)

− 0.06 (− 0.07, − 0.05)*

0.01 (− 0.004, 0.03)

TBIL (mg/dL)

− 0.44 (− 2.55, 1.66)

− 0.12 (− 0.17, − 0.07)*

0.26 (0.20, 0.33)*

PaO2/FiO2

13.3 (− 12.1, 38.7)

4.73 (2.49, 6.97)*

− 1.88 (− 4.54, 0.79)

  1. Results were expressed as β (95% CI). *P < 0.05. CI, confidence interval. FFP Transfusion indicated the difference of indexes at day 0 in FFP transfusion group compared with conventional group. Day indicated the mean of the increasing of indexes daily in conventional group. Day × FFP Transfusion indicated the average increasing of indexes daily in FFP transfusion compared with conventional group.
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