Table 3 Comparison of serum levels of Kallistatin, Nox-1, H2O2 among 6-month good CPC (CPC 1–2) and poor CPC (CPC 3–5).

From: Kallistatin deficiency exacerbates neuronal damage after cardiac arrest

 

GOOD CPC (CPC 1–2)

(N = 16)

POOR CPC (CPC 3–5)

(N = 46)

P value

At admission

 Kallistatin, μg/mL

1.01 (0.93–1.11)

0.84 (0.57–1.00)

0.011

 Nox-1, μg/L

0.60 (0.16–2.02)

2.41 (0.76–3.61)

0.013

 H2O2, μmol/L

7.91 (6.63–9.10)

8.83 (6.90–10.30)

0.210

At 24 h

 Kallistatin, μg/mL

0.91 (0.70–0.98)

0.67 (0.49–0.89)

0.034

 Nox-1, μg/L

1.08 (0.62–1.43)

2.27 (1.08–4.09)

0.020

 H2O2, μmol/L

7.05 (6.45–7.64)

7.29 (6.51–8.90)

0.247

At 72 h

 Kallistatin, μg/mL

0.77 (0.64–1.02)

0.62 (0.43–0.70)

0.001

 Nox-1, μg/L

1.17 (0.82–1.78)

2.67 (1.30–4.62)

0.011

 H2O2, μmol/L

6.82 (5.83–7.07)

7.27 (6.23–8.69)

0.038

  1. Data are presented as median (IQR).
  2. Nox-1, nicotinamide adenine dinucleotide phosphate oxidase-1; IQR, interquartile range.
  3. P values for Mann–Whitney U tests between good CPC survivors and poor CPC survivors.