Table 3 The incidence of infection and tumor in T2DM patients with different M-MDSCs frequency during follow-up period.

From: Increased monocytic myeloid-derived suppressor cells in type 2 diabetes correlate with hyperglycemic and was a risk factor of infection and tumor occurrence

Infection incidence (%)

Normal-MDSCs patients (N = 42)

High-MDSCs patients (N = 35)

P value

19.05 (8/42)

48.57 (17/35)

0.006

Urinary tract infection

4

7

 

Respiratory tract infection

4

4

 

Ocular infection

0

2

 

Oral infection

0

2

 

Intra-abdominal infection

0

2

 

Tumor incidence† (%)

0.00 (0/42)

11.43 (4/35)

0.039

Prostatic cancer

0

1

 

 Multiple myeloma

0

1

 

 Myelogenous leukemia

0

1

 

 Lung cancer

0

1

 
  1. Normal-MDSCs Patients, T2DM patients with normal M-MDSCs frequency (< 2.75%, N = 42); High-MDSCs Patients T2DM patients with high M-MDSCs frequency (≥ 2.75%, N = 35). The significance of the differences was assessed using the chi-square test or Fisher’s exact test.
  2. † Tumor incidence included patients who developed both infection and tumor during follow-up.
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