Table 1 Baseline characteristics of patients selected for the analysis—n (%) for categorical variables and mean (standard deviation—SD) for continuous variables.
From: Plasma metabolomic differences in early-onset compared to average-onset colorectal cancer
Characteristics | All CRC (n = 170) | eoCRC (n = 66) | aoCRC (n = 104) | p-valuea | Non-CRC Control (n = 49) | p-valueb |
|---|---|---|---|---|---|---|
Age (SD) | 59.4 (16.0) | 41.8 (6.1) | 70.6 (8.5) | < 0.001 | 47.4 (18.2) | NA |
Sex: Male | 101 (59.4%) | 34 (51.5%) | 67 (64.4%) | 0.131 | 8 (16.3%) | < 0.001 |
Sex: Female | 69 (40.6%) | 32 (48.5%) | 37 (35.6%) | 41 (83.7%) | ||
Race: White | 156 (91.8%) | 62 (93.9%) | 94 (90.4%) | 0.592 | 41 (83.7%) | 0.164 |
Race: Black | 12 (7.1%) | 2 (3.0%) | 10 (9.6%) | 7 (14.3%) | ||
Race: Other | 2 (1.2%) | 2 (3.0%) | 0 | 1 (2.0%) | ||
Diabetes | 35 (20.6%) | 5 (7.6%) | 30 (28.8%) | 0.002 | 5 (10.2%) | 0.148 |
Hyperlipidemia | 52 (30.6%) | 12 (18.2%) | 40 (38.5%) | 0.009 | 26 (53.1%) | 0.006 |
Obesity | 41 (24.1%) | 22 (33.3%) | 19 (18.3%) | 0.04 | 25 (51.0%) | 0.001 |
Sidedness: Left sided | 128 (75.3%) | 59 (89.4%) | 69 (66.3%) | 0.003 | - | NA |
Rectal Primary | 72 (42.4%) | 35 (53.0%) | 37 (35.6%) | 0.035 | - | NA |
Stage IV cancer | 77 (45.3%) | 41 (62.1%) | 36 (34.6%) | 0.001 | - | NA |
