Table 1 Comparison of visual function outcomes between eyes with AMD and normal controls.
By eye | Whole cohort N = 228 | All AMD N = 140 | P-value* (when compared to controls) | AREDS 1 to 3 N = 30 | P-value* (when compared to controls) | AREDS 4 N = 110 | P-value* (when compared to controls) | Control N = 66 | P-value* (when comparing between AREDS 1 to 3 and AREDS 4 subgroups) |
|---|---|---|---|---|---|---|---|---|---|
Mean retinal sensitivity dB (SD) | 22.3(7.6) | 19.2(7.6) | < 0.01 | 23.1(5.5) | < 0.01 | 18.1(7.8) | < 0.01 | 27.8(4.3) | < 0.01 |
Fixation unstable (%) | 127(55.7) | 88(62.9) | 0.02 | 18(60) | 0.19 | 70(63.6) | 0.01 | 29(43.9) | 0.39 |
Fixation area mm2 (SD) | 3.3(2.6) | 3.8(2.9) | < 0.01 | 3.4(2.2) | 0.07 | 3.9(3.0) | < 0.01 | 2.6(1.9) | 0.13 |
Fixation distance from fovea mm (SD) | 0.6(0.6) | 0.7(0.7) | < 0.01 | 0.6(0.6) | 0.07 | 0.7(0.8) | < 0.01 | 0.4(0.3) | 0.09 |
Visual acuity logMAR (SD) | 0.4(0.4) | 0.6(0.5) | < 0.01 | 0.4(0.3) | < 0.01 | 0.6(0.5) | < 0.01 | 0.2(0.2) | < 0.01 |
