Figure 5 | Scientific Reports

Figure 5

From: The gephyrin scaffold modulates cortical layer 2/3 pyramidal neuron responsiveness to single whisker stimulation

Figure 5

Spontaneous and whisker stimulation-induced activity changes in L2/3 pyramidal neurons expressing gephyrin variants. (A) Proportions of responding neurons before and after gephyrin-mutant expression in vivo are categorized based on Ca2+ transient amplitude. (B) Proportions of responding neurons before and after gephyrin-mutant expression are categorized based on the number of events (response probability). Control, n = 491 neurons; gephyrin WT, n = 643 neurons; gephyrin-K148R, n = 308 neurons; gephyrin-SSA, n = 249 neurons; gephyrin-DN, n = 204 neurons. TAM: tamoxifen. The numbers on the pie charts are rounded to one decimal place.

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