Figure 3
From: Modeling dry eye with an air–liquid interface in corneal epithelium-on-a-chip
The impact of AL stimulus on the alteration of key DE-related transcripts. (A) DEGs of mechano-stimuli, lubricant effect, inflammation, ECM remodeling, and ECM disruption. Genes with twofold change and a p-value < 0.05 was applied. (B) The comparative gene expression (normalized FPKM values) of DES markers in HCE-T cells. Dot plot in which the mean of each group is indicated with a black line (data are presented in duplicates as means ± S.E.M). The p-values were determined by the Dunnett’s multiple comparison test.
